자료유형 | 학위논문 |
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서명/저자사항 | The Role of Skin-Specific Stearoyl-CoA Desaturase-1 in Whole-Body Metabolism. |
개인저자 | Dumas, Sabrina N. |
단체저자명 | The University of Wisconsin - Madison. Nutritional Sciences. |
발행사항 | [S.l.]: The University of Wisconsin - Madison., 2018. |
발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
형태사항 | 126 p. |
기본자료 저록 | Dissertations Abstracts International 81-04B. Dissertation Abstract International |
ISBN | 9781088318546 |
학위논문주기 | Thesis (Ph.D.)--The University of Wisconsin - Madison, 2018. |
일반주기 |
Source: Dissertations Abstracts International, Volume: 81-04, Section: B.
Advisor: Ntambi, James. |
이용제한사항 | This item must not be sold to any third party vendors.This item must not be added to any third party search indexes. |
요약 | The obesity epidemic is a costly public health crisis that is not improving. In addition to the stigma and discomfort associated with carrying extra weight (at the expense of range of movement), obesity also goes hand-in-hand with co-morbidities like fatty liver disease, diabetes, cardiovascular disease, and increased risk of some forms of cancer. Currently there are no long-lasting treatments for obesity other than diet and exercise, which are not feasible for many populations that may not be equipped with the resources and/or support needed to lead a healthy lifestyle. Although there have been some pharmacological breakthroughs for treating obesity, each FDA-approved drug comes with unpleasant side-effects that make adherence unlikely. For example, Orlistat is a lipase inhibitor that prevents fat absorption in the gut. However, this leads to gastrointestinal tract issues |
일반주제명 | Nutrition. Biochemistry. Biology. |
언어 | 영어 |
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