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▼a National Academies of Sciences, Engineering, and Medicine (U.S.).
▼b Committee on the Evidence Base for Genetic Testing,
▼e author. |
| 245 | 13 |
▼a An evidence framework for genetic testing/
▼c Committee on the Evidence Base for Genetic Testing, Board on the Health of Select Populations, Board on Health Care Services, Health and Medicine Division. |
| 260 | |
▼a Washington, DC:
▼b The National Academies Press,
▼c [2017]. |
| 300 | |
▼a 1 online resource (1 PDF file (xii, 136 pages)):
▼b illustrations. |
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▼a Introduction -- Genetic testing -- Genetic test assessment -- Evidence -- An evidence framework for genetic testing -- Appendix A. Understanding genetic variance and phenotype expression -- Appendix B: the GETT checklist -- Appendix C:. Using evidence to inform clnical and policy decision -- References -- Glossary. |
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▼a Advances in genetics and genomics are transforming medical practice, resulting in a dramatic growth of genetic testing in the health care system. The rapid development of new technologies, however, has also brought challenges, including the need for rigorous evaluation of the validity and utility of genetic tests, questions regarding the best ways to incorporate them into medical practice, and how to weigh their cost against potential short- and long-term benefits. As the availability of genetic tests increases so do concerns about the achievement of meaningful improvements in clinical outcomes, costs of testing, and the potential for accentuating medical care inequality. Given the rapid pace in the development of genetic tests and new testing technologies, An Evidence Framework for Genetic Testing seeks to advance the development of an adequate evidence base for genetic tests to improve patient care and treatment. Additionally, this report recommends a framework for decision-making regarding the use of genetic tests in clinical care. |
| 536 | |
▼a This activity was supported by Contract No. HHSP233201400020B between the National Academy of Sciences and the Department of Defense. Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project. |
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▼a Online resource; title from PDF title page (viewed July 26, 2017). |
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▼a Genetic screening. |
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▼a Gene expression
▼x Testing. |
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▼a Medical genetics. |
| 650 | 0 |
▼a Human chromosome abnormalities
▼x Diagnosis. |
| 650 | 12 |
▼a Genetic Testing
▼0 https://id.nlm.nih.gov/mesh/D005820 |
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▼a Evidence-Based Medicine
▼0 https://id.nlm.nih.gov/mesh/D019317 |
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▼a Technology Assessment, Biomedical
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▼a HEALTH & FITNESS
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▼a MEDICAL
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▼a MEDICAL
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▼a MEDICAL
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▼a MEDICAL
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▼a Electronic books. |
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▼i Print version:
▼a National Academies of Sciences, Engineering, and Medicine (U.S.). Committee on the Evidence Base for Genetic Testing.
▼t Evidence framework for genetic testing.
▼d Washington, DC : the National Academies Press, [2017]
▼z 9780309453295
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