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019 ▼a 1039348348 ▼a 1039914427
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1001 ▼a Bain, Lisa J., ▼e rapporteur.
24510 ▼a Enabling novel treatments for nervous system disorders by improving methods for traversing the blood-brain barrier : ▼b proceedings of a workshop/ ▼c Lisa Bain, Noam I. Keren, and Clare Stroud, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Health and Medicine Division, the National Academies of Sciences, Engineering, Medicine.
260 ▼a Washington, DC: ▼b the National Academies Press, ▼c [2018].
300 ▼a 1 online resource (xii, 59 pages): ▼b color illustrations.
336 ▼a text ▼b txt ▼2 rdacontent
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504 ▼a Includes bibliographical references (pages 41-44).
5050 ▼a Introduction and overview --Traversing the blood-brain barrier : challenges and opportunities -- Modalities and technologies for brain delivery -- Regulatory considerations for drugs that traverse the blood-brain barrier -- Accelerating research and clinical translation : consortia and public-private partnerships -- Appendixes
520 ▼a "Despite substantial advances in developing treatments for the serious illnesses that affect people worldwide, there remains a tremendous unmet need in the treatment of complex neurologic diseases, including neuropsychiatric and neurodegenerative disorders. Chief among the challenges that have hindered the development of therapeutics for central nervous system (CNS) disorders is the blood-brain barrier (BBB). The Forum on Neuroscience and Nervous System Disorders of the National Academies of Sciences, Engineering, and Medicine convened a workshop to explore the challenges associated with the BBB that have thus far stymied development of CNS drugs, examine new technologies that could address these challenges, and highlight potential opportunities for moving the field forward. This publication summarizes the presentations and discussions from the workshop"--Publisher's description.
5880 ▼a Online resource; title from PDF title page (National Academies Press, viewed June 4, 2018).
590 ▼a Added to collection customer.56279.3
650 0 ▼a Nervous system ▼x Diseases ▼x Treatment ▼v Congresses.
650 0 ▼a Blood-brain barrier ▼v Congresses.
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650 7 ▼a Blood-brain barrier. ▼2 fast ▼0 (OCoLC)fst00834835
650 7 ▼a Nervous system ▼x Diseases ▼x Treatment. ▼2 fast ▼0 (OCoLC)fst01036124
65012 ▼a Central Nervous System Agents.
65012 ▼a Blood-Brain Barrier.
65022 ▼a Drug Design.
65022 ▼a Drug Delivery Systems.
650 2 ▼a Nervous System Diseases ▼x therapy.
655 4 ▼a Electronic books.
655 7 ▼a Conference papers and proceedings. ▼2 fast ▼0 (OCoLC)fst01423772
7001 ▼a Keren, Noam I., ▼e rapporteur,
7001 ▼a Stroud, Clare, ▼e rapporteur,
7102 ▼a National Academies of Sciences, Engineering, and Medicine (U.S.). ▼b Forum on Neuroscience and Nervous System Disorders, ▼e issuing body.
7112 ▼a Enabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Blood-Brain Barrier (Workshop) ▼d (2017 : ▼c Washington, D.C.), ▼j author.
77608 ▼i Print version: ▼a Bain, Lisa J. ▼t Enabling novel treatments for nervous system disorders by improving methods for traversing the blood짭brain barrier ▼d Washington, D.C. : National Academies Press, [2018] ▼z 9780309473071 ▼w (OCoLC)1030592949
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