LDR | | 02288nam u200457 4500 |
001 | | 000000418184 |
005 | | 20190215162642 |
008 | | 181129s2017 |||||||||||||||||c||eng d |
020 | |
▼a 9780355763287 |
035 | |
▼a (MiAaPQ)AAI10635842 |
035 | |
▼a (MiAaPQ)ucdavis:17402 |
040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 247004 |
082 | 0 |
▼a 636 |
100 | 1 |
▼a Scott, Erica Yuki Azetsu. |
245 | 10 |
▼a Molecular Pathways Underlying Cerebellar Abiotrophy in Arabian Horses. |
260 | |
▼a [S.l.]:
▼b University of California, Davis.,
▼c 2017. |
260 | 1 |
▼a Ann Arbor:
▼b ProQuest Dissertations & Theses,
▼c 2017. |
300 | |
▼a 158 p. |
500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-08(E), Section: B. |
500 | |
▼a Advisers: James D. Murray |
502 | 1 |
▼a Thesis (Ph.D.)--University of California, Davis, 2017. |
506 | |
▼a This item is not available from ProQuest Dissertations & Theses. |
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▼a Cerebellar Abiotrophy is a neurodegenerative disease with an inherited component, resulting in neurodegeneration in the cerebellum. Cerebellar abiotrophy (CA) affects Arabian horses and results in an ataxic phenotype involving uncoordinated limb |
520 | |
▼a The uncertainty revolving around the ramifications of the CA-associated SNP on the candidate genes and crucial pathways in the cerebellum drove us to investigate the transcriptome-wide differences between healthy and CA-affected horses. Pathways |
520 | |
▼a Total RNA sequencing (RNA-seq) suggested differential MUTYH isoform usage in CA-affected horses. We confirmed this using more targeted approaches of quantifying mRNA expression and uncovered differential MUTYH promoter usage as well as MUTYH pro |
590 | |
▼a School code: 0029. |
650 | 4 |
▼a Animal sciences. |
650 | 4 |
▼a Animal diseases. |
650 | 4 |
▼a Neurosciences. |
690 | |
▼a 0475 |
690 | |
▼a 0476 |
690 | |
▼a 0317 |
710 | 20 |
▼a University of California, Davis.
▼b Animal Biology. |
773 | 0 |
▼t Dissertation Abstracts International
▼g 79-08B(E). |
773 | |
▼t Dissertation Abstract International |
790 | |
▼a 0029 |
791 | |
▼a Ph.D. |
792 | |
▼a 2017 |
793 | |
▼a English |
856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14996670
▼n KERIS
▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
980 | |
▼a 201812
▼f 2019 |
990 | |
▼a ***1012033 |