| LDR | | 01987nam u200433 4500 |
| 001 | | 000000418381 |
| 005 | | 20190215162821 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438036000 |
| 035 | |
▼a (MiAaPQ)AAI10748472 |
| 035 | |
▼a (MiAaPQ)upenngdas:13127 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 247004 |
| 082 | 0 |
▼a 574 |
| 100 | 1 |
▼a Karch, Kelly R. |
| 245 | 10 |
▼a Elucidation of Histone Modifications and Nucleosomal Structure Using Novel Mass Spectrometry Approaches. |
| 260 | |
▼a [S.l.]:
▼b University of Pennsylvania.,
▼c 2018. |
| 260 | 1 |
▼a Ann Arbor:
▼b ProQuest Dissertations & Theses,
▼c 2018. |
| 300 | |
▼a 183 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B. |
| 500 | |
▼a Advisers: Benjamin A. Garcia |
| 502 | 1 |
▼a Thesis (Ph.D.)--University of Pennsylvania, 2018. |
| 520 | |
▼a The fundamental repeating unit of chromatin is the nucleosome, composed of 147 base pairs of DNA wrapped around a histone protein octamer containing two copies of H2A, H2B, H3, and H4. Histone proteins are involved in many critical nuclear proce |
| 520 | |
▼a Histone function is also mediated through its structure and dynamic properties. Hydrogen-deuterium exchange (HDX) coupled to MS is a powerful technique to monitor these properties in solution. However, traditional HDX-MS studies on histone prote |
| 590 | |
▼a School code: 0175. |
| 650 | 4 |
▼a Biochemistry. |
| 650 | 4 |
▼a Cellular biology. |
| 650 | 4 |
▼a Analytical chemistry. |
| 690 | |
▼a 0487 |
| 690 | |
▼a 0379 |
| 690 | |
▼a 0486 |
| 710 | 20 |
▼a University of Pennsylvania.
▼b Biochemistry and Molecular Biophysics. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-10B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0175 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14996989
▼n KERIS
▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a ***1012033 |