| LDR | | 02095nam u200397 4500 |
| 001 | | 000000418436 |
| 005 | | 20190215162849 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438174382 |
| 035 | |
▼a (MiAaPQ)AAI10825083 |
| 035 | |
▼a (MiAaPQ)washington:18524 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 247004 |
| 082 | 0 |
▼a 576.6 |
| 100 | 1 |
▼a Machkovech, Heather M. |
| 245 | 10 |
▼a Translation Initiation During Influenza Virus Infection and Its Role in Cellular Immunity. |
| 260 | |
▼a [S.l.]:
▼b University of Washington.,
▼c 2018. |
| 260 | 1 |
▼a Ann Arbor:
▼b ProQuest Dissertations & Theses,
▼c 2018. |
| 300 | |
▼a 160 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. |
| 500 | |
▼a Advisers: Jesse D. Bloom |
| 502 | 1 |
▼a Thesis (Ph.D.)--University of Washington, 2018. |
| 520 | |
▼a There are numerous factors that direct and constrain influenza evolution. On the one hand influenza virus is constrained to encode proteins that allow it to complete the viral life cycle, but the immune system also recognizes those same viral pr |
| 520 | |
▼a In Chapter 2, I explore one of the immune pressures that drives influenza evolution. It is well known that antibodies are a driver of the rapid evolution of influenza. However, it was unknown whether CD8 T-cells, which are also a component of ad |
| 520 | |
▼a In Chapter 3, I explore translation initiation in the context of influenza virus infection. Because CD8 T-cells shape influenza evolution and non-canonical translation initiation can generate novel CD8 T-cell epitopes, I examined whether there w |
| 590 | |
▼a School code: 0250. |
| 650 | 4 |
▼a Virology. |
| 690 | |
▼a 0720 |
| 710 | 20 |
▼a University of Washington.
▼b Genome Sciences. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-12B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0250 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14998732
▼n KERIS
▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a ***1012033 |