LDR | | 02220nam u200445 4500 |
001 | | 000000418573 |
005 | | 20190215162955 |
008 | | 181129s2018 |||||||||||||||||c||eng d |
020 | |
▼a 9780438371217 |
035 | |
▼a (MiAaPQ)AAI10843758 |
035 | |
▼a (MiAaPQ)uchicago:14512 |
040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 247004 |
082 | 0 |
▼a 574.191 |
100 | 1 |
▼a Riback, Joshua A.
▼0 (orcid)0000-0002-1516-4484. |
245 | 10 |
▼a Determinants of the Solvent Quality of Water for Disordered Proteins. |
260 | |
▼a [S.l.]:
▼b The University of Chicago.,
▼c 2018. |
260 | 1 |
▼a Ann Arbor:
▼b ProQuest Dissertations & Theses,
▼c 2018. |
300 | |
▼a 135 p. |
500 | |
▼a Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B. |
500 | |
▼a Advisers: Tobin R. Sosnick |
502 | 1 |
▼a Thesis (Ph.D.)--The University of Chicago, 2018. |
520 | |
▼a How sticky are proteins? The solvent quality, or 'stickiness', of a biomolecule has significant implications for function and homeostasis, correct calibration of molecular simulations, engineering and evolution of proteins, and much more. The so |
520 | |
▼a The demonstration that protein demixing benefits organisms is scarce yet examples of conserved demixing are common place. For example upon cellular stress, many proteins demix from the cytosol into observable foci called stress granules. In Chap |
520 | |
▼a Based on this observation, one might expect that the unfolded state of proteins also would similarly act as if it were in a poor solvent. In Chapter 3, I demonstrate that indicate that the P domain is an outlier and that the unfolded states of m |
590 | |
▼a School code: 0330. |
650 | 4 |
▼a Biophysics. |
650 | 4 |
▼a Molecular biology. |
650 | 4 |
▼a Cellular biology. |
690 | |
▼a 0786 |
690 | |
▼a 0307 |
690 | |
▼a 0379 |
710 | 20 |
▼a The University of Chicago.
▼b Biophysical Sciences. |
773 | 0 |
▼t Dissertation Abstracts International
▼g 80-01B(E). |
773 | |
▼t Dissertation Abstract International |
790 | |
▼a 0330 |
791 | |
▼a Ph.D. |
792 | |
▼a 2018 |
793 | |
▼a English |
856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14999944
▼n KERIS
▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
980 | |
▼a 201812
▼f 2019 |
990 | |
▼a ***1012033 |