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020 ▼a 9780438092570
035 ▼a (MiAaPQ)AAI10871469
035 ▼a (MiAaPQ)OhioLINK:osu1492735573118956
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 247004
0820 ▼a 610
1001 ▼a Clark, Elizabeth S.
24510 ▼a Models and Mechanisms to Evaluate Tissue Engineered Vascular Graft Stenosis.
260 ▼a [S.l.]: ▼b The Ohio State University., ▼c 2017.
260 1 ▼a Ann Arbor: ▼b ProQuest Dissertations & Theses, ▼c 2017.
300 ▼a 165 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
500 ▼a Adviser: Christopher Breuer.
5021 ▼a Thesis (Ph.D.)--The Ohio State University, 2017.
520 ▼a Congenital heart disease represents the most common form of birth defect and is present in up to 1% of all live births. Of particular interest to our group is the treatment of single ventricle disease, specifically hypoplastic left heart syndrom
520 ▼a The long-term goal of this project is to develop a second-generation composite vascular graft for use in children. The objective of this study is to elucidate the mechanism of TEVG neotissue formation in immunocompetent mice (Mus musculus) and c
520 ▼a Previous research by our lab C57BL/6 mice has suggested that the transforming growth factor-beta (TGF-beta)/Smad2-3 pathway is involved in the development of TEVG stenosis. While the specific role of the TGF-beta pathway in the development of st
590 ▼a School code: 0168.
650 4 ▼a Biomedical engineering.
650 4 ▼a Medicine.
650 4 ▼a Pathology.
650 4 ▼a Medical imaging.
650 4 ▼a Biology.
690 ▼a 0541
690 ▼a 0564
690 ▼a 0571
690 ▼a 0574
690 ▼a 0306
71020 ▼a The Ohio State University. ▼b Comparative and Veterinary Medicine.
7730 ▼t Dissertation Abstracts International ▼g 79-10B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0168
791 ▼a Ph.D.
792 ▼a 2017
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000231 ▼n KERIS ▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다.
980 ▼a 201812 ▼f 2019
990 ▼a ***1012033