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020 ▼a 9780438125940
035 ▼a (MiAaPQ)AAI10902988
035 ▼a (MiAaPQ)umichrackham:001146
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 247004
0820 ▼a 547
1001 ▼a Ngernsutivorakul, Thitaphat.
24510 ▼a Microfabricated Sampling Probes for Monitoring Brain Chemistry at High Spatial and Temporal Resolution.
260 ▼a [S.l.]: ▼b University of Michigan., ▼c 2018.
260 1 ▼a Ann Arbor: ▼b ProQuest Dissertations & Theses, ▼c 2018.
300 ▼a 215 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
500 ▼a Adviser: Robert T. Kennedy.
5021 ▼a Thesis (Ph.D.)--University of Michigan, 2018.
520 ▼a Monitoring neurochemical dynamics has played a crucial role in elucidating brain function and related disorders. An essential approach for monitoring neurochemicals is to couple sampling probes to analytical measurements
520 ▼a Conventional sampling probes were handmade and have several disadvantages, including large sizes (over 220 mum in diameter) and limited design flexibility. To address these disadvantages, we have used microfabrication to manufacture sampling pro
520 ▼a Furthermore, we have continued the development of a microfabricated push-pull probe. We enhanced functionality of the probe by integrating an additional channel into the probe for chemical delivery. Further, we demonstrated that the probe can fe
520 ▼a This collection of work illustrates that development of the microfabricated sampling probes and their compatible microfluidic systems are highly beneficial for studying brain chemistry. The integrated miniaturized analytical technology can poten
590 ▼a School code: 0127.
650 4 ▼a Organic chemistry.
650 4 ▼a Neurosciences.
690 ▼a 0490
690 ▼a 0317
71020 ▼a University of Michigan. ▼b Chemistry.
7730 ▼t Dissertation Abstracts International ▼g 79-12B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0127
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000496 ▼n KERIS ▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다.
980 ▼a 201812 ▼f 2019
990 ▼a ***1012033