| LDR | | 02418nam u200409 4500 |
| 001 | | 000000419471 |
| 005 | | 20190215163713 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438271593 |
| 035 | |
▼a (MiAaPQ)AAI10840498 |
| 035 | |
▼a (MiAaPQ)wisc:15526 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 247004 |
| 082 | 0 |
▼a 574 |
| 100 | 1 |
▼a Turton, Keren B. |
| 245 | 10 |
▼a Case Studies of Cryptic Proteins Contributing to Shape Change in Eosinophils: Workflows to Investigate STAT3, LOCGEF and NHSL2. |
| 260 | |
▼a [S.l.]:
▼b The University of Wisconsin - Madison.,
▼c 2018. |
| 260 | 1 |
▼a Ann Arbor:
▼b ProQuest Dissertations & Theses,
▼c 2018. |
| 300 | |
▼a 263 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. |
| 500 | |
▼a Adviser: Deane F. Mosher. |
| 502 | 1 |
▼a Thesis (Ph.D.)--The University of Wisconsin - Madison, 2018. |
| 520 | |
▼a Following interleukin-5 stimulation, eosinophils rapidly become acorn-shaped. The bi-lobed nucleus is propelled to the cone of the acorn, termed the "nucleopod". By integrating eosinophil immunostaining with (phospho)proteomics data |
| 520 | |
▼a Signal transducer and activator of transcription 3 (STAT3) is an important regulator of transcription in activated leukocytes. An unexpected STAT3 isoform peptide, lacking a single residue (Ser701) led to the questions, what are the relative pro |
| 520 | |
▼a We describe the "LOCGEFs", a set of leukocyte-specific spliceforms of ARHGEF18, a guanine nucleotide exchange factor. These proteins were discovered because the proteomics dataset included peptides mapping to a protein annotated as LOC100996504. |
| 520 | |
▼a Nance-Horan Syndrome-like protein 2 (NHSL2) was one of the most profoundly altered proteins after IL5 treatment: within 5 minutes, the fold-phosphorylation at 4 sites increased dramatically. Nearly nothing is published about this protein, so we |
| 590 | |
▼a School code: 0262. |
| 650 | 4 |
▼a Biochemistry. |
| 690 | |
▼a 0487 |
| 710 | 20 |
▼a The University of Wisconsin - Madison.
▼b Biomolecular Chemistry. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-12B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0262 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14999730
▼n KERIS
▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a ***1012033 |