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020 ▼a 9781088332429
035 ▼a (MiAaPQ)AAI13904710
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 247004
0820 ▼a 150
1001 ▼a Satyshur, Maureen Doyle.
24510 ▼a Subtypes of Rumination Associated with White Matter Integrity in Women with Depression.
260 ▼a [S.l.]: ▼b Northwestern University., ▼c 2019.
260 1 ▼a Ann Arbor: ▼b ProQuest Dissertations & Theses, ▼c 2019.
300 ▼a 57 p.
500 ▼a Source: Dissertations Abstracts International, Volume: 81-04, Section: B.
500 ▼a Advisor: Gollan, Jacqueline K.
5021 ▼a Thesis (Ph.D.)--Northwestern University, 2019.
506 ▼a This item must not be sold to any third party vendors.
520 ▼a Recent studies have begun to examine white matter connectivity aberrations in psychiatric populations, such as major depressive disorder. Several studies have found reduced white matter integrity (WMI) in depressed samples, though the location of this reduction is not clear. Incorporating symptom measures of depression severity and rumination may allow for increased identification and localization of aberrant WMI in this heterogeneous disorder. This study examined WMI, specifically fractional anisotropy (FA), using diffusion tensor imaging in a sample of depressed adult women (N=45). The relationship between depression severity and subscales of rumination with fractional anisotropy in six tracts were analyzed, including the bilateral superior longitudinal fasciculus, bilateral uncinate fasciculus, and bilateral cingulum bundle. Increased reflective rumination was associated with increased FA in the right cingulum bundle and left uncinate fasciculus. Additionally, post-hoc analyses considered other measures of WMI in those two tracts. Results found that depression rumination and brooding rumination were associated with aberrant WMI in the left uncinate fasciculus. Findings from this study offer a unique understanding of how white matter integrity in prefrontal, temporal, and limbic regions may be associated with different forms of rumination in women diagnosed with major depression.
590 ▼a School code: 0163.
650 4 ▼a Clinical psychology.
650 4 ▼a Neurosciences.
650 4 ▼a Psychology.
690 ▼a 0622
690 ▼a 0317
690 ▼a 0621
71020 ▼a Northwestern University. ▼b Clinical Psychology.
7730 ▼t Dissertations Abstracts International ▼g 81-04B.
773 ▼t Dissertation Abstract International
790 ▼a 0163
791 ▼a Ph.D.
792 ▼a 2019
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15492560 ▼n KERIS ▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다.
980 ▼a 202002 ▼f 2020
990 ▼a ***1008102
991 ▼a E-BOOK