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020 ▼a 9781088318119
035 ▼a (MiAaPQ)AAI13903022
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 247004
0820 ▼a 616
1001 ▼a Nicholson, W Chance.
24510 ▼a Vagal Mediated Heart Rate Variability and Cognitive Impairments in HIV-Seropositive Women.
260 ▼a [S.l.]: ▼b The University of Alabama at Birmingham., ▼c 2019.
260 1 ▼a Ann Arbor: ▼b ProQuest Dissertations & Theses, ▼c 2019.
300 ▼a 190 p.
500 ▼a Source: Dissertations Abstracts International, Volume: 81-04, Section: B.
500 ▼a Advisor: Vance, David E.
5021 ▼a Thesis (Ph.D.)--The University of Alabama at Birmingham, 2019.
506 ▼a This item must not be sold to any third party vendors.
506 ▼a This item must not be added to any third party search indexes.
520 ▼a Regardless of sufficient viral suppression, HIV exerts an ongoing inflammatory process that promotes chronic autonomic nervous system (ANS) dysfunction, accelerates physiological aging, and increases the risk of developing a spectrum of cognitive disorders (known as HIV-associated neurocognitive disorders [HAND]). Given this, identifying pathological mediators of this inflammatory response could provide insight into the mechanisms driving HAND. The vagus nerve (indexed by vagal-mediated heart rate variability [vmHRV]) could provide such a mediator as it regulates ANS activity via reciprocal cardio-neural pathways, which regulate inflammation and homeostasis. Vagal dysfunction is associated with persistent inflammatory signaling (e.g., stress or inflammatory-based disorders [such as HIV]), emotional dysregulation, and cognitive impairments. Chronically reduced vmHRV indices are observed in HIV-seropositive (SP) persons
590 ▼a School code: 0005.
650 4 ▼a Psychobiology.
690 ▼a 0349
71020 ▼a The University of Alabama at Birmingham. ▼b Nursing.
7730 ▼t Dissertations Abstracts International ▼g 81-04B.
773 ▼t Dissertation Abstract International
790 ▼a 0005
791 ▼a Ph.D.
792 ▼a 2019
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15492418 ▼n KERIS ▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다.
980 ▼a 202002 ▼f 2020
990 ▼a ***1008102
991 ▼a E-BOOK