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020 ▼a 9781088317976
035 ▼a (MiAaPQ)AAI13903096
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 247004
0820 ▼a 618.97
1001 ▼a Nilakantan, Aneesha Sekhar.
24510 ▼a Recollection Precision: Neural Mechanisms and Modulation via Network-Targeted Brain Stimulation.
260 ▼a [S.l.]: ▼b Northwestern University., ▼c 2019.
260 1 ▼a Ann Arbor: ▼b ProQuest Dissertations & Theses, ▼c 2019.
300 ▼a 106 p.
500 ▼a Source: Dissertations Abstracts International, Volume: 81-04, Section: B.
500 ▼a Advisor: Voss, Joel L
5021 ▼a Thesis (Ph.D.)--Northwestern University, 2019.
506 ▼a This item must not be sold to any third party vendors.
506 ▼a This item must not be added to any third party search indexes.
520 ▼a Episodic memory provides a means by which we are able to reflect on the past, make decisions about the future, and form a learned identity. Even subtle changes to our memory can have a detrimental impact on our daily lives. Memory declines as we age, and clinically salient impairment is one of the defining symptoms of amnestic mild cognitive impairment and diagnosis of dementia due to Alzheimer's disease. As a result, decades of research have been dedicated to unpacking the mechanisms by which the brain, specifically the hippocampus, supports the formation and retrieval of different forms of memory. However, recollection memory is typically tested using all-or-nothing measures of general success that fail to capture the quality and details (precision) of the memory recalled. Here, I present a series of experiments combing noninvasive neuroimaging techniques with behavioral paradigms that utilize novel analysis approaches, in order to characterize the precision of recollection. Results from these experiments demonstrate that recollection precision is critically dependent on the hippocampus, relies on a distributed cortical network, is a sensitive measure that selectively captures impairment due to age, and can be improved via noninvasive stimulation.
590 ▼a School code: 0163.
650 4 ▼a Neurosciences.
650 4 ▼a Cognitive psychology.
650 4 ▼a Aging.
690 ▼a 0317
690 ▼a 0633
690 ▼a 0493
71020 ▼a Northwestern University. ▼b Interdepartmental Neuroscience Program (NUIN).
7730 ▼t Dissertations Abstracts International ▼g 81-04B.
773 ▼t Dissertation Abstract International
790 ▼a 0163
791 ▼a Ph.D.
792 ▼a 2019
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15492429 ▼n KERIS ▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다.
980 ▼a 202002 ▼f 2020
990 ▼a ***1008102
991 ▼a E-BOOK