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020 ▼a 9781085679145
035 ▼a (MiAaPQ)AAI13899906
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 247004
0820 ▼a 157
1001 ▼a Seaman, Lauren Catherine.
24510 ▼a Leveraging the Tools and Techniques of Precision Medicine to Better Understand the Biological Underpinnings of Psychiatric Disorders and Psychotropic Treatment Effects.
260 ▼a [S.l.]: ▼b University of California, Los Angeles., ▼c 2019.
260 1 ▼a Ann Arbor: ▼b ProQuest Dissertations & Theses, ▼c 2019.
300 ▼a 328 p.
500 ▼a Source: Dissertations Abstracts International, Volume: 81-02, Section: B.
500 ▼a Advisor: Nurmi, Erika L.
5021 ▼a Thesis (Ph.D.)--University of California, Los Angeles, 2019.
506 ▼a This item must not be sold to any third party vendors.
520 ▼a The dawn of a new era of medicine has begun as clinicians and researchers shift their focus to more individual-centric diagnostic, treatment, and disease management strategies. Precision medicine is a multidisciplinary approach to human health care that takes into account a person's genetic makeup, behaviors, and environmental factors when evaluating pathophysiology, tailoring treatments, and designing novel therapeutic moieties. In this dissertation I break down the critical subfields of this discipline to explain and apply the emerging tools and techniques we now have at our disposal to better understand the underlying biology of complex human psychiatric disorders.We begin with pharmacokinetics and pharmacodynamics, two branches of precision medicine that are involved directly with the temporal dynamics of pharmaceutical therapies and aid in disentanglement of how the body processes drugs versus how the drugs affect our bodies. I discuss detailed research across three separate drugs
590 ▼a School code: 0031.
650 4 ▼a Organic chemistry.
650 4 ▼a Pharmacology.
650 4 ▼a Medicine.
650 4 ▼a Clinical psychology.
690 ▼a 0490
690 ▼a 0419
690 ▼a 0564
690 ▼a 0622
71020 ▼a University of California, Los Angeles. ▼b Chemistry 0153.
7730 ▼t Dissertations Abstracts International ▼g 81-02B.
773 ▼t Dissertation Abstract International
790 ▼a 0031
791 ▼a Ph.D.
792 ▼a 2019
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15492127 ▼n KERIS ▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다.
980 ▼a 202002 ▼f 2020
990 ▼a ***1008102
991 ▼a E-BOOK