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008200131s2019 ||||||||||||||||| ||eng d
020 ▼a 9781085796880
035 ▼a (MiAaPQ)AAI13895840
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 247004
0820 ▼a 616
1001 ▼a Shasha, Carolyn.
24510 ▼a Nonequilibrium Nanoparticle Dynamics for the Development of Magnetic Particle Imaging.
260 ▼a [S.l.]: ▼b University of Washington., ▼c 2019.
260 1 ▼a Ann Arbor: ▼b ProQuest Dissertations & Theses, ▼c 2019.
300 ▼a 212 p.
500 ▼a Source: Dissertations Abstracts International, Volume: 81-04, Section: B.
500 ▼a Advisor: Krishnan, Kannan M.
5021 ▼a Thesis (Ph.D.)--University of Washington, 2019.
506 ▼a This item must not be sold to any third party vendors.
506 ▼a This item must not be added to any third party search indexes.
520 ▼a Magnetic Particle Imaging (MPI) is a promising new medical imaging platform currently in the preclinical stage. MPI uses iron oxide nanoparticles as tracers, and exploits their nonlinear magnetization response to external oscillating magnetic fields. The nanoparticle response is directly measured to create an image in MPI, and so optimizing nanoparticle properties as well as external magnetic field conditions in order to obtain improved image signal is crucial to the development of MPI as a clinical platform. A deep understanding of the physics of nanoparticle relaxation is fundamental to optimization and further development of MPI.This work focuses on modeling the nonequilibrium dynamics of magnetic nanoparticles in order to optimize conditions for MPI and develop new therapeutic and diagnostic functionalities that can be integrated with MPI. A summary of theoretical models of nanoparticle dynamics is presented, and computational nonequilibrium models are outlined, which currently represent the most sophisticated methods for modeling nanoparticle dynamics. These models are verified and supported through experiment. Using these models, nanoparticle relaxation is explored in depth
590 ▼a School code: 0250.
650 4 ▼a Physics.
650 4 ▼a Nanotechnology.
650 4 ▼a Medical imaging.
690 ▼a 0605
690 ▼a 0652
690 ▼a 0574
71020 ▼a University of Washington. ▼b Physics.
7730 ▼t Dissertations Abstracts International ▼g 81-04B.
773 ▼t Dissertation Abstract International
790 ▼a 0250
791 ▼a Ph.D.
792 ▼a 2019
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15491650 ▼n KERIS ▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다.
980 ▼a 202002 ▼f 2020
990 ▼a ***1008102
991 ▼a E-BOOK