LDR | | 00000nam u2200205 4500 |
001 | | 000000433062 |
005 | | 20200225111822 |
008 | | 200131s2019 ||||||||||||||||| ||eng d |
020 | |
▼a 9781085776936 |
035 | |
▼a (MiAaPQ)AAI13809457 |
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▼a MiAaPQ
▼c MiAaPQ
▼d 247004 |
082 | 0 |
▼a 531 |
100 | 1 |
▼a Bergel, Guy Leshem. |
245 | 10 |
▼a A Finite Element Method for Modeling Surface Growth and Resorption of Deformable Bodies with Applications to Cell Migration. |
260 | |
▼a [S.l.]:
▼b University of California, Berkeley.,
▼c 2019. |
260 | 1 |
▼a Ann Arbor:
▼b ProQuest Dissertations & Theses,
▼c 2019. |
300 | |
▼a 117 p. |
500 | |
▼a Source: Dissertations Abstracts International, Volume: 81-04, Section: B. |
500 | |
▼a Advisor: Papadopoulos, Panayiotis |
502 | 1 |
▼a Thesis (Ph.D.)--University of California, Berkeley, 2019. |
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▼a This item must not be sold to any third party vendors. |
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▼a Surface growth/resorption is the process wherein material is added to or removed from the boundary of a physical body. As a consequence, the set of material points constituting the body is time-dependent and thus lacks a static reference configuration. In this dissertation, kinematics and balance laws are formulated for a body undergoing surface growth/resorption and finite deformation. This is achieved by defining an evolving reference configuration termed the intermediate configuration which tracks the set of material points constituting the body at a given time.An extension of the Arbitrary Lagrangian-Eulerian finite element method is introduced to solve the discretized set of balance laws on the grown/resorpted body, alongside algorithmic implementations to track the evolving boundary of the physical body. The effect of accreting material with no prior history of deformation onto a body undergoing rigid motions as well as a loaded body is discussed. Moreover, the correlation between growth/resorption rate and the spatial and temporal convergence of the finite element approximations of fields are illustrated.The numerical implementation for surface growth and resorption is used to simulate a migrating cell which moves in an apparent "treadmilling" motion on a substrate by polymerizing and de-polymerizing microfilaments along its boundary. An example is presented which defines a surface growth law based on the nucleation and dissociation of chemical species, and the steady-state treadmilling velocity is computed for various assumed cell shapes. Lastly, simulation results are shown for an idealized cell colliding with external barriers, leading to a re-orientation of the surface growth/resorption direction. The effects of dynamic contact on the surface growth/resorption as well as the stress and deformation are discussed. |
590 | |
▼a School code: 0028. |
650 | 4 |
▼a Civil engineering. |
650 | 4 |
▼a Mechanical engineering. |
650 | 4 |
▼a Mechanics. |
690 | |
▼a 0543 |
690 | |
▼a 0548 |
690 | |
▼a 0346 |
710 | 20 |
▼a University of California, Berkeley.
▼b Civil and Environmental Engineering. |
773 | 0 |
▼t Dissertations Abstracts International
▼g 81-04B. |
773 | |
▼t Dissertation Abstract International |
790 | |
▼a 0028 |
791 | |
▼a Ph.D. |
792 | |
▼a 2019 |
793 | |
▼a English |
856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15490596
▼n KERIS
▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
980 | |
▼a 202002
▼f 2020 |
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▼a ***1816162 |
991 | |
▼a E-BOOK |