| LDR | | 00000nam u2200205 4500 |
| 001 | | 000000433538 |
| 005 | | 20200225143252 |
| 008 | | 200131s2019 ||||||||||||||||| ||eng d |
| 020 | |
▼a 9781088336298 |
| 035 | |
▼a (MiAaPQ)AAI22583477 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 247004 |
| 082 | 0 |
▼a 574 |
| 100 | 1 |
▼a Wu, Meng. |
| 245 | 10 |
▼a Investigating the Genomic Basis of Novel Trait Evolution Using Evolutionary Genomics. |
| 260 | |
▼a [S.l.]:
▼b Indiana University.,
▼c 2019. |
| 260 | 1 |
▼a Ann Arbor:
▼b ProQuest Dissertations & Theses,
▼c 2019. |
| 300 | |
▼a 147 p. |
| 500 | |
▼a Source: Dissertations Abstracts International, Volume: 81-05, Section: B. |
| 500 | |
▼a Advisor: Moyle, Leonie C. |
| 502 | 1 |
▼a Thesis (Ph.D.)--Indiana University, 2019. |
| 506 | |
▼a This item must not be sold to any third party vendors. |
| 520 | |
▼a Comparative genetic analyses of closely related species with phenotypic diversity have been used to identify the genetic changes associated with recent trait evolution. The recent emergence of whole genome or transcriptome sequencing allows us to investigate the associated genetic changes in genome-wide level, from thousands to millions of sites in coding or noncoding regions. Through analyzing genome-wide data, I studied the genetic basis of several interesting traits (i.e. fruit color variation, floral shape diversity, and sex determination) in some plants species within the hyper-diverse Solanaceae family. First, I analyzed whole-transcriptome data from 14 species within a rapidly radiation clade (the genus Jaltomata) to identify some candidate genes with genetic variants in their coding regions, potentially associated with fruit color variation or floral shape diversity. Next, I generated a genome assembly for one representative species of Jaltomata (J. sinuosa) and then compared this genome with other previously annotated genomes in Solanaceae (e.g. potato, tomato, pepper), from which I inferred Jaltomata-specific changes in both coding and non-coding regions potentially associated with floral shape evolution. Finally, I examined a recently dioecious plant species (Solanum appendiculatum) with separate males and females in the population. Through examining the RNA-seq and whole genome sequencing data from dozens of male and female individuals, I detected a gene regulation pathway that could be potentially involved in the sex determination in this species. Overall, these findings from my research works would provide valuable genomic resources and insights for further investigation and understanding of the genetic mechanisms responsible for trait evolution within this ecologically, economically important plant families Solanaceae. |
| 590 | |
▼a School code: 0093. |
| 650 | 4 |
▼a Evolution & development. |
| 690 | |
▼a 0412 |
| 710 | 20 |
▼a Indiana University.
▼b Biology. |
| 773 | 0 |
▼t Dissertations Abstracts International
▼g 81-05B. |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0093 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2019 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15492786
▼n KERIS
▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
| 980 | |
▼a 202002
▼f 2020 |
| 990 | |
▼a ***1008102 |
| 991 | |
▼a E-BOOK |