| LDR | | 00000nam u2200205 4500 |
| 001 | | 000000433712 |
| 005 | | 20200225153050 |
| 008 | | 200131s2019 ||||||||||||||||| ||eng d |
| 020 | |
▼a 9781085652537 |
| 035 | |
▼a (MiAaPQ)AAI22615713 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 247004 |
| 082 | 0 |
▼a 540 |
| 100 | 1 |
▼a Johnson, Keywan A. |
| 245 | 10 |
▼a Advancements in Nickel-Catalyzed Cross-Electrophile Coupling. |
| 260 | |
▼a [S.l.]:
▼b The University of Wisconsin - Madison.,
▼c 2019. |
| 260 | 1 |
▼a Ann Arbor:
▼b ProQuest Dissertations & Theses,
▼c 2019. |
| 300 | |
▼a 180 p. |
| 500 | |
▼a Source: Dissertations Abstracts International, Volume: 81-03, Section: B. |
| 500 | |
▼a Advisor: Weix, Daniel J. |
| 502 | 1 |
▼a Thesis (Ph.D.)--The University of Wisconsin - Madison, 2019. |
| 506 | |
▼a This item must not be sold to any third party vendors. |
| 506 | |
▼a This item must not be added to any third party search indexes. |
| 520 | |
▼a In this thesis, the extension of cross-electrophile coupling to engage vinyl halides, organic chlorides, and dihalides for cyclization will be described in detail.Chapter 1 will provide an introduction to cross-electrophile coupling and the current state of the art for these transformations.Chapter 2 describes the development of improved coupling conditions for the nickel-catalyzed cross-electrophile coupling of vinyl halides with alkyl halides. The application of these conditions to aryl-alkyl coupling, substrate scope and limitations, and preliminary mechanistic insights are also discussed.Chapter 3 describes studies performed for the coupling of aryl and alkyl chlorides. The effects of a dual ligand system on reaction selectivity, as well as implications of dimethoxyethane and diglyme nickel precatalysts are also conferred.Chapter 4 provides a survey of macrocyclization methodologies and details the application of cross-electrophile coupling to the synthesis of macrocyclic rings. Efforts towards the total synthesis of (짹)-Recifeiolide are also discussed. |
| 590 | |
▼a School code: 0262. |
| 650 | 4 |
▼a Organic chemistry. |
| 650 | 4 |
▼a Chemistry. |
| 690 | |
▼a 0490 |
| 690 | |
▼a 0485 |
| 710 | 20 |
▼a The University of Wisconsin - Madison.
▼b Chemistry. |
| 773 | 0 |
▼t Dissertations Abstracts International
▼g 81-03B. |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0262 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2019 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15493322
▼n KERIS
▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
| 980 | |
▼a 202002
▼f 2020 |
| 990 | |
▼a ***1008102 |
| 991 | |
▼a E-BOOK |