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020 ▼a 9781088345313
035 ▼a (MiAaPQ)AAI22584795
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 247004
0820 ▼a 636
1001 ▼a Perez, Alice.
24510 ▼a Neurogenesis Is Altered between and across Brain Regions after Neurodegeneration and Injury.
260 ▼a [S.l.]: ▼b City University of New York., ▼c 2019.
260 1 ▼a Ann Arbor: ▼b ProQuest Dissertations & Theses, ▼c 2019.
300 ▼a 137 p.
500 ▼a Source: Dissertations Abstracts International, Volume: 81-04, Section: B.
500 ▼a Advisor: Pytte, Carolyn.
5021 ▼a Thesis (Ph.D.)--City University of New York, 2019.
506 ▼a This item must not be sold to any third party vendors.
520 ▼a Adult neurogenesis is the addition of new neurons in the adult brain. In mammals, neurogenesis is largely restricted to the hippocampus and olfactory bulb, which underlie learning, memory, and olfaction. In songbirds, new neurons are incorporated into telencephalic regions that subserve the production, perception, and maintenance of song. Studies of the regulation of neurogenesis have exclusively focused on a single brain region and within a single hemisphere. Interestingly, it has yet to be investigated whether there are correlations between numbers of new neurons across regions and hemispheres within the same animal. Here we examined these differences in a rat model of a neurodegenerative disease and in songbirds with peripheral nerve damage. We found that neurogenesis is regulated across brain regions and within hemispheres of both animal models. An understanding of how neurogenesis is impacted across and within healthy and diseased brains may lead to strategies that consider interconnected effects in a whole brain system to help promote neurogenesis, which may ultimately mitigate cognitive impairment.
590 ▼a School code: 0046.
650 4 ▼a Behavioral sciences.
650 4 ▼a Neurosciences.
650 4 ▼a Animal sciences.
690 ▼a 0602
690 ▼a 0317
690 ▼a 0475
71020 ▼a City University of New York. ▼b Psychology.
7730 ▼t Dissertations Abstracts International ▼g 81-04B.
773 ▼t Dissertation Abstract International
790 ▼a 0046
791 ▼a Ph.D.
792 ▼a 2019
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15492882 ▼n KERIS ▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다.
980 ▼a 202002 ▼f 2020
990 ▼a ***1008102
991 ▼a E-BOOK