LDR | | 00000nam u2200205 4500 |
001 | | 000000434294 |
005 | | 20200226145057 |
008 | | 200131s2019 ||||||||||||||||| ||eng d |
020 | |
▼a 9781392762523 |
035 | |
▼a (MiAaPQ)AAI22616978 |
040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 247004 |
082 | 0 |
▼a 547 |
100 | 1 |
▼a Moore, Lucas Charles. |
245 | 10 |
▼a Diastereoselective Additions of Anhydride Enolates and Nucleophilic Alkenes to Chiral Aldehyde-derived N-Tosyl Imines. |
260 | |
▼a [S.l.]:
▼b University of California, Davis.,
▼c 2019. |
260 | 1 |
▼a Ann Arbor:
▼b ProQuest Dissertations & Theses,
▼c 2019. |
300 | |
▼a 236 p. |
500 | |
▼a Source: Dissertations Abstracts International, Volume: 81-06, Section: B. |
500 | |
▼a Advisor: Shaw, Jared T. |
502 | 1 |
▼a Thesis (Ph.D.)--University of California, Davis, 2019. |
506 | |
▼a This item must not be sold to any third party vendors. |
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▼a Described herein are the detailed approaches towards several synthetic organic chemistry projects. Chapter one describes the development of a new formal [4 + 2] cycloaddition reaction involving enolizable anhydrides and N-sulfonyl imines. During the course of these studies, we observed unexpected diastereoselectivity when using chiral aldehyde-derived N- sulfonyl imines. Chapter two details an investigation into this unexpected diastereoselectivity and subsequent development of a Lewis acid-mediated diastereodivergent reaction. Chapter three describes the complex synthesis of the chiral N-sulfonyl imines used as substrates in chapters one and two. Chapter four details two partially successful total synthesis efforts towards structurally related marine natural products, chrysophaentin E and colpol. Finally, chapter five describes the synthesis of three DNA gyrase inhibitors, gyramides E-F, as well as the methods used to synthesize their precursors. |
590 | |
▼a School code: 0029. |
650 | 4 |
▼a Organic chemistry. |
690 | |
▼a 0490 |
710 | 20 |
▼a University of California, Davis.
▼b Chemistry. |
773 | 0 |
▼t Dissertations Abstracts International
▼g 81-06B. |
773 | |
▼t Dissertation Abstract International |
790 | |
▼a 0029 |
791 | |
▼a Ph.D. |
792 | |
▼a 2019 |
793 | |
▼a English |
856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15493434
▼n KERIS
▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
980 | |
▼a 202002
▼f 2020 |
990 | |
▼a ***1008102 |
991 | |
▼a E-BOOK |