| LDR | | 00000nam u2200205 4500 |
| 001 | | 000000435375 |
| 005 | | 20200228093908 |
| 008 | | 200131s2019 ||||||||||||||||| ||eng d |
| 020 | |
▼a 9781088343203 |
| 035 | |
▼a (MiAaPQ)AAI13810976 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 247004 |
| 082 | 0 |
▼a 591 |
| 100 | 1 |
▼a Peterson, Kristin Rose. |
| 245 | 10 |
▼a Immunometabolism and the Role of Complement Factor 5 in Insulin Action. |
| 260 | |
▼a [S.l.]:
▼b Vanderbilt University.,
▼c 2019. |
| 260 | 1 |
▼a Ann Arbor:
▼b ProQuest Dissertations & Theses,
▼c 2019. |
| 300 | |
▼a 134 p. |
| 500 | |
▼a Source: Dissertations Abstracts International, Volume: 81-04, Section: B. |
| 500 | |
▼a Advisor: Wadzinski, Brian. |
| 502 | 1 |
▼a Thesis (Ph.D.)--Vanderbilt University, 2019. |
| 506 | |
▼a This item must not be sold to any third party vendors. |
| 506 | |
▼a This item must not be added to any third party search indexes. |
| 520 | |
▼a Adipose tissue (AT) is a dynamic endocrine organ that contributes to metabolic health. Proper function of resident immune cells is vital to AT function, and thus the pro-inflammatory AT environment during obesity contributes to disease. Brown AT functions differently than white AT, and burns energy through thermogenesis rather than storing lipid. This Dissertation discusses what is known about immune cells in white AT, discoveries our lab has made in regards to the prevalence of immune cells in brown AT, and then focuses on a potential role for complement factor 5 (C5) in insulin action. C5 control (C5cont) and C5 deficient (C5def) mice were placed on low and high fat diets to investigate their inflammatory and metabolic phenotypes. C5def mice gained less weight while fed a high fat diet |
| 590 | |
▼a School code: 0242. |
| 650 | 4 |
▼a Immunology. |
| 650 | 4 |
▼a Physiology. |
| 650 | 4 |
▼a Endocrinology. |
| 690 | |
▼a 0982 |
| 690 | |
▼a 0719 |
| 690 | |
▼a 0409 |
| 710 | 20 |
▼a Vanderbilt University.
▼b Pharmacology. |
| 773 | 0 |
▼t Dissertations Abstracts International
▼g 81-04B. |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0242 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2019 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15490671
▼n KERIS
▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
| 980 | |
▼a 202002
▼f 2020 |
| 990 | |
▼a ***1816162 |
| 991 | |
▼a E-BOOK |