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020 ▼a 9781088318546
035 ▼a (MiAaPQ)AAI10934153
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 247004
0820 ▼a 574
1001 ▼a Dumas, Sabrina N.
24514 ▼a The Role of Skin-Specific Stearoyl-CoA Desaturase-1 in Whole-Body Metabolism.
260 ▼a [S.l.]: ▼b The University of Wisconsin - Madison., ▼c 2018.
260 1 ▼a Ann Arbor: ▼b ProQuest Dissertations & Theses, ▼c 2018.
300 ▼a 126 p.
500 ▼a Source: Dissertations Abstracts International, Volume: 81-04, Section: B.
500 ▼a Advisor: Ntambi, James.
5021 ▼a Thesis (Ph.D.)--The University of Wisconsin - Madison, 2018.
506 ▼a This item must not be sold to any third party vendors.
506 ▼a This item must not be added to any third party search indexes.
520 ▼a The obesity epidemic is a costly public health crisis that is not improving. In addition to the stigma and discomfort associated with carrying extra weight (at the expense of range of movement), obesity also goes hand-in-hand with co-morbidities like fatty liver disease, diabetes, cardiovascular disease, and increased risk of some forms of cancer. Currently there are no long-lasting treatments for obesity other than diet and exercise, which are not feasible for many populations that may not be equipped with the resources and/or support needed to lead a healthy lifestyle. Although there have been some pharmacological breakthroughs for treating obesity, each FDA-approved drug comes with unpleasant side-effects that make adherence unlikely. For example, Orlistat is a lipase inhibitor that prevents fat absorption in the gut. However, this leads to gastrointestinal tract issues
590 ▼a School code: 0262.
650 4 ▼a Nutrition.
650 4 ▼a Biochemistry.
650 4 ▼a Biology.
690 ▼a 0570
690 ▼a 0487
690 ▼a 0306
71020 ▼a The University of Wisconsin - Madison. ▼b Nutritional Sciences.
7730 ▼t Dissertations Abstracts International ▼g 81-04B.
773 ▼t Dissertation Abstract International
790 ▼a 0262
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15490362 ▼n KERIS ▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다.
980 ▼a 202002 ▼f 2020
990 ▼a ***1816162
991 ▼a E-BOOK