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020 ▼a 9781392551585
035 ▼a (MiAaPQ)AAI27680149
035 ▼a (MiAaPQ)NCState_Univ18402036925
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 247004
0820 ▼a 636
1001 ▼a Silva Guillen, Ysenia Victoria.
24510 ▼a Antioxidant Supplementation to Alleviate the Negative Effects of Heat and Oxidative Stress on Performance and Health of Nursery and Growing Pigs.
260 ▼a [S.l.]: ▼b North Carolina State University., ▼c 2019.
260 1 ▼a Ann Arbor: ▼b ProQuest Dissertations & Theses, ▼c 2019.
300 ▼a 190 p.
500 ▼a Source: Dissertations Abstracts International, Volume: 81-05, Section: B.
500 ▼a Advisor: Lanzas, Cristina
5021 ▼a Thesis (Ph.D.)--North Carolina State University, 2019.
506 ▼a This item must not be sold to any third party vendors.
520 ▼a The present dissertation evaluated the supplementation of vitamin E, polyphenols or phytogenics in feed or drinking water on growth performance, immune and oxidative status in growing pigs housed under heat stress and in weaned piglets fed peroxidized oil diets. In study 1 (Chapter II) the impact of antioxidants on growth, intestinal morphology, hematology indices, immune and oxidative status in growing pigs housed under heat stress was evaluated in 2 replicated experiments. In each experiment, 64 crossbred pigs were used, with an initial body weight (BW) of 50.7짹3.8 kg and 43.9짹 3.6 and age of 13-weeks and 12-weeks old for each experiment, respectively. Individually housed pigs were assigned within weight blocks and sex to a 2 x 4 factorial arrangement consisting of 2 environments (thermo-neutral (21.2째C) or heat-stressed (30.9째C)) and 4 supplementation treatments (control, control+vitamin E in water, control+vitamin E in feed, and control+polyphenols in feed). Heat stress reduced growth, but no effects of supplementation were found. Intestinal morphology was not affected by heat stress or supplementation or their interaction. Intestinal cellular proliferation was increased in pigs supplemented with vitamin E in feed and water during heat stress. Serum and liver vitamin E were increased with vitamin E supplementation, especially when supplemented in water. Serum malondialdehyde (MDA), an oxidative stress marker, was greater with antioxidant supplementation compared with control, and on d 2 vs. d 28. MDA in ileal mucosa was increased when using dietary vitamin E and polyphenols. Immune status evaluated using serum cytokines was not impacted by heat stress or supplementation. Red blood cells, hemoglobin and hematocrit percentage were reduced by heat stress when measured on d 28. White blood cells, platelets, and monocyte counts were reduced on d 28 vs. d 2. In the study 2 (Chapter III), the effects of dietary vitamin E and polyphenols on growth, and immune and oxidative status in weaned piglets was evaluated. Pigs (n=192
590 ▼a School code: 0155.
650 4 ▼a Livestock.
650 4 ▼a Animal sciences.
690 ▼a 0475
71020 ▼a North Carolina State University.
7730 ▼t Dissertations Abstracts International ▼g 81-05B.
773 ▼t Dissertation Abstract International
790 ▼a 0155
791 ▼a Ph.D.
792 ▼a 2019
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15494657 ▼n KERIS ▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다.
980 ▼a 202002 ▼f 2020
990 ▼a ***1816162
991 ▼a E-BOOK