| LDR | | 00000nam u2200205 4500 |
| 001 | | 000000436618 |
| 005 | | 20200228145556 |
| 008 | | 200131s2018 ||||||||||||||||| ||eng d |
| 020 | |
▼a 9781687923929 |
| 035 | |
▼a (MiAaPQ)AAI10933331 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 247004 |
| 082 | 0 |
▼a 614 |
| 100 | 1 |
▼a Vangay, Pajau. |
| 245 | 10 |
▼a Gut Microbiome Westernization in Hmong and Karen Refugees and Immigrants in the United States. |
| 260 | |
▼a [S.l.]:
▼b University of Minnesota.,
▼c 2018. |
| 260 | 1 |
▼a Ann Arbor:
▼b ProQuest Dissertations & Theses,
▼c 2018. |
| 300 | |
▼a 145 p. |
| 500 | |
▼a Source: Dissertations Abstracts International, Volume: 81-04, Section: B. |
| 500 | |
▼a Advisor: Knights, Dan. |
| 502 | 1 |
▼a Thesis (Ph.D.)--University of Minnesota, 2018. |
| 506 | |
▼a This item must not be sold to any third party vendors. |
| 506 | |
▼a This item must not be added to any third party search indexes. |
| 520 | |
▼a Many United States immigrant populations develop metabolic diseases post-immigration, but the causes are not well understood. Although the microbiome plays a role in metabolic disease, there have been no studies measuring the effects of U.S. immigration on the gut microbiome. We collected stool, dietary recalls, and anthropometrics from 514 Hmong and Karen individuals living in Thailand and the U.S., including first- and second-generation immigrants and 19 Karen individuals sampled before and after immigration, as well as from 36 U.S.-born Caucasian individuals. Using 16S and deep shotgun metagenomic DNA sequencing, we found that migration from a non-Western country to the U.S. is associated with immediate loss of gut microbiome diversity and function, with U.S.-associated strains and functions displacing native strains and functions. These effects increase with duration of U.S. residence, and are compounded by obesity and across generations. |
| 590 | |
▼a School code: 0130. |
| 650 | 4 |
▼a Microbiology. |
| 650 | 4 |
▼a Bioinformatics. |
| 650 | 4 |
▼a Public health. |
| 690 | |
▼a 0410 |
| 690 | |
▼a 0715 |
| 690 | |
▼a 0573 |
| 710 | 20 |
▼a University of Minnesota.
▼b Biomedical Informatics and Computational Biology. |
| 773 | 0 |
▼t Dissertations Abstracts International
▼g 81-04B. |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0130 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15490357
▼n KERIS
▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
| 980 | |
▼a 202002
▼f 2020 |
| 990 | |
▼a ***1008102 |
| 991 | |
▼a E-BOOK |