| LDR | | 00000nam u2200205 4500 |
| 001 | | 000000436705 |
| 005 | | 20200228151441 |
| 008 | | 200131s2018 ||||||||||||||||| ||eng d |
| 020 | |
▼a 9781088311028 |
| 035 | |
▼a (MiAaPQ)AAI10809678 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 247004 |
| 082 | 0 |
▼a 616 |
| 100 | 1 |
▼a Wallace, Jared Andrew. |
| 245 | 14 |
▼a The Role of MicroRNAs in Promoting FLT3-ITD-Induced Myeloid Malignancy. |
| 260 | |
▼a [S.l.]:
▼b The University of Utah.,
▼c 2018. |
| 260 | 1 |
▼a Ann Arbor:
▼b ProQuest Dissertations & Theses,
▼c 2018. |
| 300 | |
▼a 88 p. |
| 500 | |
▼a Source: Dissertations Abstracts International, Volume: 81-04, Section: B. |
| 500 | |
▼a Advisor: O'Connell, Ryan. |
| 502 | 1 |
▼a Thesis (Ph.D.)--The University of Utah, 2018. |
| 506 | |
▼a This item must not be sold to any third party vendors. |
| 520 | |
▼a MicroRNA expression is dysregulated in many human cancers, including hematopoietic malignancies. Among hematopoietic malignancies, acute myeloid leukemia (AML) carries a particularly poor prognosis, leading to over 10,000 deaths each year in the US alone. The most common genetic aberration in AML is a gain-of-function mutation in the FMS-like tyrosine kinase 3 (FLT3) receptor. FLT3 internal tandem duplication (ITD) occurs in ~30% of all AML cases, and confers a negative prognosis. MicroRNA expression has been shown to be highly dysregulated in FLT3-ITD+ AML |
| 590 | |
▼a School code: 0240. |
| 650 | 4 |
▼a Oncology. |
| 650 | 4 |
▼a Molecular biology. |
| 650 | 4 |
▼a Immunology. |
| 690 | |
▼a 0992 |
| 690 | |
▼a 0307 |
| 690 | |
▼a 0982 |
| 710 | 20 |
▼a The University of Utah.
▼b Pathology. |
| 773 | 0 |
▼t Dissertations Abstracts International
▼g 81-04B. |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0240 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15490298
▼n KERIS
▼z 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
| 980 | |
▼a 202002
▼f 2020 |
| 990 | |
▼a ***1008102 |
| 991 | |
▼a E-BOOK |