| LDR | | 03899cam a2200553Ii 4500 |
| 001 | | 000000480315 |
| 005 | | 20230210094526 |
| 006 | | m d |
| 007 | | cr cnu---unuuu |
| 008 | | 220708s2022 mau ob 001 0 eng d |
| 020 | |
▼a 9780262370028
▼q (electronic bk.) |
| 020 | |
▼a 0262370026
▼q (electronic bk.) |
| 020 | |
▼z 9780262046947 |
| 020 | |
▼z 0262046946 |
| 035 | |
▼a 3160177
▼b (N$T) |
| 035 | |
▼a (OCoLC)1334725183 |
| 037 | |
▼a 14366
▼b MIT Press |
| 037 | |
▼a 9780262370028
▼b MIT Press |
| 040 | |
▼a MITPR
▼b eng
▼e rda
▼e pn
▼c MITPR
▼d YDX
▼d EBLCP
▼d N$T
▼d 247004 |
| 050 | 4 |
▼a R853.A53
▼b S77 2022eb |
| 082 | 04 |
▼a 616.02/7
▼2 23/eng/20220708 |
| 100 | 1 |
▼a Striedter, Georg F.,
▼d 1962-
▼e author. |
| 245 | 10 |
▼a Model systems in biology :
▼b history, philosophy, and practical concerns/
▼c Georg Striedter. |
| 264 | 1 |
▼a Cambridge, Massachusetts :
▼b The MIT Press,
▼c [2022] |
| 300 | |
▼a 1 online resource (1 volume). |
| 336 | |
▼a text
▼b txt
▼2 rdacontent |
| 337 | |
▼a computer
▼b c
▼2 rdamedia |
| 338 | |
▼a online resource
▼b cr
▼2 rdacarrier |
| 504 | |
▼a Includes bibliographical references and index. |
| 505 | 0 |
▼a Intro -- Contents -- Preface -- 1. Crises in Biomedical Research -- 1.1 The Translatability Crisis -- 1.2 The Replicability Crisis -- 1.3 Reckoning with Biological Variation -- 1.4 Which Model Is "Best"? -- 1.5 This Book's Approach and Organization -- 2. Philosophy of Models in Biology -- 2.1 Abstract Models -- 2.2 Material Models -- 2.3 Assumptions about Model Fidelity -- 2.4 Dealing with Biological Complexity -- 2.5 Animal Welfare and Cognitive Dissonance -- 2.6 Comparative Biology and August Krogh Revisited -- 3. A History of Animal Models -- 3.1 Eclectic Beginnings of Biology |
| 505 | 8 |
▼a 3.2 Early Experimental Medicine: Research on Pet Species -- 3.3 Fruit Flies: The First Supermodel -- 3.4 Laboratory Rats: The First Standardized Mammals -- 3.5 Laboratory Mice: From Cancer Fighter to Model Organism -- 3.6 Nonhuman Primates -- 3.7 The Rest of the Menagerie -- 3.8 Model System Ecology -- 4. A History of in Vitro Models -- 4.1 Microbial Models -- 4.2 Cell and Tissue Culture Models -- 4.3 Alternative Models in Toxicology -- 4.4 Model Ecology Revisited -- 5. Models and Therapies: Infectious Diseases, Cardiovascular Disease, and Cancer -- 5.1 Infectious Diseases |
| 505 | 8 |
▼a 5.2 Cardiovascular Diseases -- 5.3 Cancers -- 5.4 Patterns of Model Use -- 6. Neurological Disorders: Trials and Tribulations -- 6.1 Brain and Spinal Cord Injuries -- 6.2 Neurodegenerative Disorders -- 6.3 Neuropsychiatric Disorders -- 6.4 Successes, Failures, Hopes -- 7. Diagnosis and Recommendations -- 7.1 Four Perspectives on Models in Biology -- 7.2 Recommendations -- 7.3 Conclusion -- Appendix -- References -- Index |
| 520 | |
▼a "Instead of arguing for a specific animal model, Striedter will review the history and philosophy of animal models in biomedical research, examining their various advantages and limitations"--
▼c Provided by publisher. |
| 588 | 0 |
▼a Print version record. |
| 590 | |
▼a Added to collection customer.56279.3 |
| 650 | 0 |
▼a Animal models in research. |
| 650 | 0 |
▼a Animal experimentation. |
| 650 | 2 |
▼a Animal Experimentation
▼0 (DNLM)D032761 |
| 650 | 6 |
▼a Mode?les animaux dans la recherche.
▼0 (CaQQLa)201-0127335 |
| 650 | 6 |
▼a Expe?rimentation animale.
▼0 (CaQQLa)201-0001372 |
| 650 | 7 |
▼a Animal experimentation.
▼2 fast
▼0 (OCoLC)fst00809161 |
| 650 | 7 |
▼a Animal models in research.
▼2 fast
▼0 (OCoLC)fst00809302 |
| 655 | 4 |
▼a Electronic books. |
| 776 | 08 |
▼i Print version:
▼a Striedter, Georg F., 1962-
▼t Model systems in biology.
▼d Cambridge, Massachusetts : The MIT Press, [2022]
▼z 9780262046947
▼w (DLC) 2021033979
▼w (OCoLC)1272882517 |
| 856 | 40 |
▼3 EBSCOhost
▼u https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=3160177 |
| 938 | |
▼a EBSCOhost
▼b EBSC
▼n 3160177 |
| 990 | |
▼a ***1818828 |
| 991 | |
▼a E-BOOK |
| 994 | |
▼a 92
▼b N$T |