상세정보
Export to Refworks부가기능
Arterial and Venous Impacts of Transdermally Administered Vasodilators on the Local Microvasculature
상세 프로파일
| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Arterial and Venous Impacts of Transdermally Administered Vasodilators on the Local Microvasculature. |
| 개인저자 | Guo, George. |
| 단체저자명 | Yale University. Yale School of Medicine. |
| 발행사항 | [S.l.]: Yale University., 2017. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2017. |
| 형태사항 | 32 p. |
| 기본자료 저록 | Dissertation Abstracts International 79-11B(E). Dissertation Abstract International |
| ISBN | 9780438132092 |
| 학위논문주기 | Thesis (M.D.)--Yale University, 2017. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Adviser: David Silverman. |
| 요약 | Microcirculatory function is an important component of cardiovascular pharmacology as related to cardiovascular dysfunction. We used photoplethysmography (PPG) to compare the microcirculatory effects of transdermal patches of rivastigmine (Exelo |
| 요약 | Methods: With IRB approval, 10 healthy volunteers were monitored with PPG at the time each transdermal patch was applied and every 8 minutes afterwards for a total of 40 minutes. 1x1 cm portions of patches of rivastigmine, nicotine, and NTG were |
| 요약 | Results: The max DeltaAC change for each drug were significantly different from that of its control while only the max DeltaDC of NTG was significantly greater than that of its control. Changes in the DeltaAC/DeltaDC ratio were found to be incon |
| 요약 | Discussion: These results may provide some insight into the cardiovascular effects of the study agents used. NTG, a direct NO donor, caused significant increases in AC (arteriolar) and DC (venous) values. Acting at the pre/post ganglionic juncti |
| 일반주제명 | Medicine. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
