자료유형 | 학위논문 |
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서명/저자사항 | Innovative Microbial Outcomes in Randomized Control Trials. |
개인저자 | Ray, Kathryn. |
단체저자명 | University of California, San Francisco. Epidemiology and Translational Science. |
발행사항 | [S.l.]: University of California, San Francisco., 2018. |
발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
형태사항 | 76 p. |
기본자료 저록 | Dissertation Abstracts International 79-12B(E). Dissertation Abstract International |
ISBN | 9780438250369 |
학위논문주기 | Thesis (Ph.D.)--University of California, San Francisco, 2018. |
일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Thomas M. Lietman. |
요약 | Randomized Control Trials (RCTs) in infectious disease can use a clinical outcome or a microbiological surrogate outcome. While caregivers are more interested in the clinical outcome, the microbiological outcome may be far more sensitive. Here I |
요약 | In chapter one, I design and analyze an experiment to compare community microbiome diversity estimates derived from 16s rRNA sequencing of 1) individually sequenced specimens versus 2) pooled specimens collected from a community. I then compare |
요약 | The estimates of community level microbiome diversity from pooled samples correlated well with estimates from individual samples. Additionally, all pooled samples fell within the 95% limits of agreement. Pooling microbiome samples to estimate co |
일반주제명 | Epidemiology. Public health. |
언어 | 영어 |
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: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |