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The Role of Myosin X in BMPs Promotion of SMAD 1/5 in Osteoclast Formation and Function

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서명/저자사항The Role of Myosin X in BMPs Promotion of SMAD 1/5 in Osteoclast Formation and Function.
개인저자Tasca, Amy Ward.
단체저자명University of Minnesota. Oral Biology.
발행사항[S.l.]: University of Minnesota., 2017.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2017.
형태사항105 p.
기본자료 저록Dissertation Abstracts International 80-01B(E).
Dissertation Abstract International
ISBN9780438353114
학위논문주기Thesis (Ph.D.)--University of Minnesota, 2017.
일반주기 Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Adviser: Kim Mansky.
요약Novel therapeutic strategies that target osteoclasts are needed for many orthopedic, craniofacial and cancer applications. Incomplete understanding of the factors that regulate osteoclasts limits this development. Currently, bone morphogenetic p
요약The data presented in this thesis demonstrates that loss of SMAD1/5 expression by osteoclasts in in vitro cultures of osteoclasts inhibits osteoclast differentiation and activity. However, the loss of SMAD1/5 expression in osteoclasts and macrop
일반주제명Biology.
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