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Understanding the Motility of Molecular Motors Using Theory and Simulations
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Understanding the Motility of Molecular Motors Using Theory and Simulations. |
| 개인저자 | Goldtzvik, Yonathan. |
| 단체저자명 | University of Maryland, College Park. Biophysics. |
| 발행사항 | [S.l.]: University of Maryland, College Park., 2017. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2017. |
| 형태사항 | 160 p. |
| 기본자료 저록 | Dissertation Abstracts International 79-07B(E). Dissertation Abstract International |
| ISBN | 9780355629057 |
| 학위논문주기 | Thesis (Ph.D.)--University of Maryland, College Park, 2017. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-07(E), Section: B.
Adviser: Devarajan Thirumalai. |
| 이용제한사항 | This item is not available from ProQuest Dissertations & Theses. |
| 요약 | Molecular motors are indispensable machines that are in charge of transporting cargoes within living cells. Despite recent advances in the study of these molecules, there is much that we still do not understand regarding the underlying mechanism |
| 요약 | Dynein is a large motor that transports cargo along microtubules towards their negative pole. Unlike other motors, such as conventional kinesin, the motility of dynein is highly stochastic. We developed a novel theoretical approach, which reprod |
| 요약 | A less understood aspect of dynein is the complex set of allosteric transitions in response to ATP binding and hydrolysis, and microtubule binding. The resulting conformational transitions propel the motor forward to the minus end of the microtu |
| 요약 | Kinesins are highly processive motor proteins that transport cargo along microtubules toward their positive poles. Experiments show that the kinesin motor domains propel the motor forward by passing each other in a hand-over-hand motion. However |
| 일반주제명 | Biophysics. Biology. Molecular physics. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
