상세정보
Export to Refworks부가기능
Investigation of Interaction Between Peptide and Lipid Bilayer by Molecular Dynamics Simulation
상세 프로파일
| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Investigation of Interaction Between Peptide and Lipid Bilayer by Molecular Dynamics Simulation. |
| 개인저자 | Xiang, Ning. |
| 단체저자명 | Purdue University. Agricultural and Biological Engineering. |
| 발행사항 | [S.l.]: Purdue University., 2017. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2017. |
| 형태사항 | 152 p. |
| 기본자료 저록 | Dissertation Abstracts International 79-07B(E). Dissertation Abstract International |
| ISBN | 9780355613582 |
| 학위논문주기 | Thesis (Ph.D.)--Purdue University, 2017. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-07(E), Section: B.
Adviser: Ganesan Narsimhan. |
| 이용제한사항 | This item is not available from ProQuest Dissertations & Theses. |
| 요약 | Antimicrobial peptides (AMPs) inactivate microbial cells through pore formation in cell membrane. Because of their different mode of action compared to antibiotics, AMPs can be effectively used to combat drug resistant bacteria in human health. |
| 요약 | The effects of (i) number of total and net charges, (ii) hydrophobicity (iii) hydrophobic moment and (iv) helicity of peptides from soy protein on their ability to bind to lipid bilayer and their transmembrane aggregates to form pores were inves |
| 요약 | MD simulation was also employed to investigation interaction between amyloid beta (Abeta) peptide and lipid bilayer. Some amyloid-related proteins/peptides are involved in aggregation and pore formation in phospholipid membranes (cell membranes) |
| 일반주제명 | Agricultural engineering. Food science. Computational chemistry. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
