자료유형 | 학위논문 |
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서명/저자사항 | Discovery of Novel TAF1 DNA Binding Domains in TFIID Promoter Recognition and Gene Transcription. |
개인저자 | Curran, Elizabeth C. |
단체저자명 | University of Washington. Pharmacology. |
발행사항 | [S.l.]: University of Washington., 2017. |
발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2017. |
형태사항 | 108 p. |
기본자료 저록 | Dissertation Abstracts International 79-05B(E). Dissertation Abstract International |
ISBN | 9780355597882 |
학위논문주기 | Thesis (Ph.D.)--University of Washington, 2017. |
일반주기 |
Source: Dissertation Abstracts International, Volume: 79-05(E), Section: B.
Advisers: Edith Wang |
이용제한사항 | This item is not available from ProQuest Dissertations & Theses. |
요약 | The central dogma of biology describes the basic flow of genetic information starting from DNA, which is converted to message RNA, then into functional proteins. This classical view provides a framework for how a cell can respond to its environm |
요약 | Presented here is the discovery of two DNA binding domains (DBDs) in TAF1, the largest TFIID subunit. This work identified and characterized two previously unknown DBDs, the winged helix (WH) located in the central DUF3591 domain and the evoluti |
일반주제명 | Molecular biology. Pharmacology. |
언어 | 영어 |
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