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Ovarian Carcinoma in Jaguars (Panthera onca): Investigating the Genetic Mechanisms of Tumorigenesis
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Ovarian Carcinoma in Jaguars (Panthera onca): Investigating the Genetic Mechanisms of Tumorigenesis. |
| 개인저자 | Corner, Sarah. |
| 단체저자명 | Michigan State University. Pathobiology. |
| 발행사항 | [S.l.]: Michigan State University., 2018. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
| 형태사항 | 222 p. |
| 기본자료 저록 | Dissertation Abstracts International 79-12B(E). Dissertation Abstract International |
| ISBN | 9780438248380 |
| 학위논문주기 | Thesis (Ph.D.)--Michigan State University, 2018. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Dalen Agnew. |
| 요약 | Jaguars are near threatened throughout their entire geographic range and endangered in the United States. Wild jaguars are threatened by habitat loss and other human impacts, and maintaining a healthy breeding population in zoological institutio |
| 요약 | We performed a retrospective analysis of reproductive tract and mammary gland lesions from 56 jaguars housed in North American zoological institutions and found a high prevalence (26 of 49 jaguars |
| 요약 | To elucidate the genetic mechanisms of ovarian carcinoma in jaguars, we first assessed the genetic diversity of the North American zoo population overall compared to reported wild jaguar populations. Using novel universal primer sequences, we cr |
| 요약 | To evaluate candidate cancer genes for germline mutations associated with ovarian carcinoma, we used a targeted next generation sequencing approach to sequence the coding regions of 276 cancer genes in paired ovarian carcinoma and normal jaguar |
| 일반주제명 | Pathology. Oncology. Zoology. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
