자료유형 | 학위논문 |
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서명/저자사항 | Structural Basis of Vertebrate Vision, a G Protein-Coupled Receptor Signaling Cascade. |
개인저자 | Gao, Yang. |
단체저자명 | Cornell University. Chemistry & Chemical Biology. |
발행사항 | [S.l.]: Cornell University., 2018. |
발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
형태사항 | 167 p. |
기본자료 저록 | Dissertation Abstracts International 80-01B(E). Dissertation Abstract International |
ISBN | 9780438343245 |
학위논문주기 | Thesis (Ph.D.)--Cornell University, 2018. |
일반주기 |
Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Adviser: Richard A. Cerione. |
요약 | The visual photo-transduction cascade is a prototypical G protein-coupled receptor (GPCR) signaling system, in which light-activated rhodopsin, the GPCR, catalyzes the exchange of GDP for GTP on the heterotrimeric G protein transducin. This resu |
요약 | Recent X-ray and cryo-electron microscopy (cryo-EM) structures of complexes between different GPCRs and the stimulatory GS protein have revealed how these receptors converge structurally at the cytoplasmic end and engage the same GS protein, whe |
일반주제명 | Chemistry. Biochemistry. Biophysics. |
언어 | 영어 |
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