자료유형 | 학위논문 |
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서명/저자사항 | Synthetic Study of Amphidinolides C, C2, C3, and F: Construction of the C1--C9 and the C10--C25 Building Blocks. |
개인저자 | Akwaboah, Daniel Clement. |
단체저자명 | The Ohio State University. Chemistry. |
발행사항 | [S.l.]: The Ohio State University., 2017. |
발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2017. |
형태사항 | 333 p. |
기본자료 저록 | Dissertation Abstracts International 79-12B(E). Dissertation Abstract International |
ISBN | 9780438098381 |
학위논문주기 | Thesis (Ph.D.)--The Ohio State University, 2017. |
일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Craig Forsyth. |
요약 | Amphidinolides C, C2, C3, and F are cytotoxic secondary metabolites that occur naturally from symbiotic marine dinoflagellates Amphidinium sp. from the Okinawan flatworm. They share an identical 25-membered macrolide core that possesses 11 ster |
요약 | Our contribution to the amphidinolide project was designed to assemble a common macrolide framework which could be elaborated with minimal synthetic manipulations to access all four target molecules. We recognized a hidden structural homology th |
일반주제명 | Chemistry. Organic chemistry. |
언어 | 영어 |
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