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Chromatin Structure Changes During Terminal Differentiation and Cell Cycle Exit in Drosophila melanogaster

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서명/저자사항Chromatin Structure Changes During Terminal Differentiation and Cell Cycle Exit in Drosophila melanogaster.
개인저자Ma, Yiqin.
단체저자명University of Michigan. Molecular, Cellular, and Developmental Biology.
발행사항[S.l.]: University of Michigan., 2018.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2018.
형태사항170 p.
기본자료 저록Dissertation Abstracts International 79-12B(E).
Dissertation Abstract International
ISBN9780438126244
학위논문주기Thesis (Ph.D.)--University of Michigan, 2018.
일반주기 Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Laura Buttitta.
요약During development, the number of cell divisions must be precisely controlled in order to produce tissues of the correct shape, composition and size. The majority of cells complete their final cell cycle during a process called terminal differen
요약To examine the relationship between cell cycle exit and chromatin structure during terminal differentiation, I characterized the temporal changes in chromatin accessibility and gene expression during the process of terminal differentiation in th
요약Higher order chromatin organization such as the clustering of heterochromatin in the nucleus is also impacted by cell cycle exit and terminal differentiation. I found that heterochromatin clusters as cells exit the cell cycle and terminally diff
일반주제명Cellular biology.
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