자료유형 | 학위논문 |
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서명/저자사항 | Chromatin Structure Changes During Terminal Differentiation and Cell Cycle Exit in Drosophila melanogaster. |
개인저자 | Ma, Yiqin. |
단체저자명 | University of Michigan. Molecular, Cellular, and Developmental Biology. |
발행사항 | [S.l.]: University of Michigan., 2018. |
발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
형태사항 | 170 p. |
기본자료 저록 | Dissertation Abstracts International 79-12B(E). Dissertation Abstract International |
ISBN | 9780438126244 |
학위논문주기 | Thesis (Ph.D.)--University of Michigan, 2018. |
일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Laura Buttitta. |
요약 | During development, the number of cell divisions must be precisely controlled in order to produce tissues of the correct shape, composition and size. The majority of cells complete their final cell cycle during a process called terminal differen |
요약 | To examine the relationship between cell cycle exit and chromatin structure during terminal differentiation, I characterized the temporal changes in chromatin accessibility and gene expression during the process of terminal differentiation in th |
요약 | Higher order chromatin organization such as the clustering of heterochromatin in the nucleus is also impacted by cell cycle exit and terminal differentiation. I found that heterochromatin clusters as cells exit the cell cycle and terminally diff |
일반주제명 | Cellular biology. |
언어 | 영어 |
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: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |