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Micro-Engineered Devices for Point-of-Care Blood Clot Retraction Testing
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Micro-Engineered Devices for Point-of-Care Blood Clot Retraction Testing. |
| 개인저자 | Li, Zida. |
| 단체저자명 | University of Michigan. Mechanical Engineering. |
| 발행사항 | [S.l.]: University of Michigan., 2018. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
| 형태사항 | 108 p. |
| 기본자료 저록 | Dissertation Abstracts International 79-12B(E). Dissertation Abstract International |
| ISBN | 9780438126442 |
| 학위논문주기 | Thesis (Ph.D.)--University of Michigan, 2018. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Jianping Fu. |
| 요약 | Blood coagulation is a critical hemostatic process that must be properly regulated to maintain the delicate balance between bleeding and clotting. Disorders of blood coagulation can expose patients to the risk of either bleeding disorders or thr |
| 요약 | This thesis aims to leverage advances in micro-technology and functional soft materials to develop miniaturized devices for clot retraction force measurements, providing accurate and reliable blood coagulation assays with potentials for point-of |
| 요약 | First, I designed a force-sensing device, named Miniaturized Hemoretractometer (mHRM), based on image acquisition and analysis to measure contraction force generated during blood clotting. This clot retraction force served as an indicator of coa |
| 요약 | Acquiring electrical signals instead of images could vastly simplify the instrumentation of mHRM. However, integrating conductive materials into soft elastomer (PDMS) was a challenge. To address this problem, I developed a method to coat carbon |
| 요약 | Finally, I applied this CNT deposition method into the design of mHRM and developed a CNT strain sensor based mHRM (CNT-mHRM). I investigated the parameters that affected the sensitivity of CNT-mHRM devices and demonstrated that CNT-mHRM generat |
| 일반주제명 | Mechanical engineering. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
