자료유형 | 학위논문 |
---|---|
서명/저자사항 | Comparison of Transcriptional Activation of Epstein-Barr Virus and Cellular Gene Expression by ZEBRA and Mutant Cellular AP-1 Proteins. |
개인저자 | Lyons, Danielle Elizabeth. |
단체저자명 | Yale University. |
발행사항 | [S.l.]: Yale University., 2018. |
발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
형태사항 | 118 p. |
기본자료 저록 | Dissertation Abstracts International 79-11B(E). Dissertation Abstract International |
ISBN | 9780438194076 |
학위논문주기 | Thesis (Ph.D.)--Yale University, 2018. |
일반주기 |
Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Adviser: I. George Miller. |
요약 | The ubiquitous gamma herpes virus, Epstein-Barr virus (EBV), has latent and lytic phases in its life cycle. The EBV ZEBRA protein activates the EBV lytic cycle from latency. Previous work has shown that the homologous cellular AP-1 proteins, c-J |
요약 | Previous work characterizing the ability of AP-1(A/S) to activate expression of EBV genes has been limited. In order to characterize the overall pattern of expression of viral genes by ZEBRA and AP-1(A/S), I performed an EBV gene array. I presen |
일반주제명 | Virology. Microbiology. Genetics. |
언어 | 영어 |
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