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Comparison of Transcriptional Activation of Epstein-Barr Virus and Cellular Gene Expression by ZEBRA and Mutant Cellular AP-1 Proteins

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서명/저자사항Comparison of Transcriptional Activation of Epstein-Barr Virus and Cellular Gene Expression by ZEBRA and Mutant Cellular AP-1 Proteins.
개인저자Lyons, Danielle Elizabeth.
단체저자명Yale University.
발행사항[S.l.]: Yale University., 2018.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2018.
형태사항118 p.
기본자료 저록Dissertation Abstracts International 79-11B(E).
Dissertation Abstract International
ISBN9780438194076
학위논문주기Thesis (Ph.D.)--Yale University, 2018.
일반주기 Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Adviser: I. George Miller.
요약The ubiquitous gamma herpes virus, Epstein-Barr virus (EBV), has latent and lytic phases in its life cycle. The EBV ZEBRA protein activates the EBV lytic cycle from latency. Previous work has shown that the homologous cellular AP-1 proteins, c-J
요약Previous work characterizing the ability of AP-1(A/S) to activate expression of EBV genes has been limited. In order to characterize the overall pattern of expression of viral genes by ZEBRA and AP-1(A/S), I performed an EBV gene array. I presen
일반주제명Virology.
Microbiology.
Genetics.
언어영어
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