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The Temporal Relationship between Synucleinopathy, Nigrostriatal Degeneration, and Neuroinflammation in the Alpha-Synuclein Preformed Fibril Model of Parkinson's Disease
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | The Temporal Relationship between Synucleinopathy, Nigrostriatal Degeneration, and Neuroinflammation in the Alpha-Synuclein Preformed Fibril Model of Parkinson's Disease. |
| 개인저자 | Duffy, Megan Frances. |
| 단체저자명 | Michigan State University. Neuroscience - Doctor of Philosophy. |
| 발행사항 | [S.l.]: Michigan State University., 2018. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
| 형태사항 | 195 p. |
| 기본자료 저록 | Dissertation Abstracts International 79-12B(E). Dissertation Abstract International |
| ISBN | 9780438286658 |
| 학위논문주기 | Thesis (Ph.D.)--Michigan State University, 2018. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Caryl E. Sortwell. |
| 요약 | Numerous studies have documented risk variants in immune genes and increased microglial inflammatory markers in the parenchyma and biofluids of Parkinson's disease (PD) patients. Recently our lab has characterized a new rat model of PD induced b |
| 요약 | First, I histologically examined the time course of synucleinopathy, microgliosis and nigral degeneration at monthly intervals. Microglia in the vicinity of Lewy body-like inclusions display significantly increased cell body area and observable |
| 일반주제명 | Neurosciences. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
