자료유형 | 학위논문 |
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서명/저자사항 | Analysis of Resting-State Neurovascular Coupling and Locomotion-Associated Neural Dynamics Using Wide-Field Optical Mapping. |
개인저자 | Ma, Ying. |
단체저자명 | Columbia University. Biomedical Engineering. |
발행사항 | [S.l.]: Columbia University., 2018. |
발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
형태사항 | 170 p. |
기본자료 저록 | Dissertation Abstracts International 79-12B(E). Dissertation Abstract International |
ISBN | 9780438281325 |
학위논문주기 | Thesis (Ph.D.)--Columbia University, 2018. |
일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Elizabeth M. C. Hillman. |
요약 | Understanding the relationship between neural activity and cortical hemodynamics, or neurovascular coupling is the foundation to interpret neuroimaging signals such as functional magnetic resonance imaging (fMRI) which measure local changes in h |
요약 | To directly assess the cortical neurovascular coupling, simultaneous recordings of neural and hemodynamic activity were imaged by wide-field optical mapping (WFOM) over the bilateral dorsal surface of the mouse brain through a bilateral thinned- |
요약 | A linear model between neural and hemodynamic signals was used to fit spatiotemporal hemodynamics can be predicted by convolving local fluorescence changes with hemodynamic response functions derived through both deconvolution and gamma-variate |
일반주제명 | Biomedical engineering. |
언어 | 영어 |
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