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Analysis of Resting-State Neurovascular Coupling and Locomotion-Associated Neural Dynamics Using Wide-Field Optical Mapping

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서명/저자사항Analysis of Resting-State Neurovascular Coupling and Locomotion-Associated Neural Dynamics Using Wide-Field Optical Mapping.
개인저자Ma, Ying.
단체저자명Columbia University. Biomedical Engineering.
발행사항[S.l.]: Columbia University., 2018.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2018.
형태사항170 p.
기본자료 저록Dissertation Abstracts International 79-12B(E).
Dissertation Abstract International
ISBN9780438281325
학위논문주기Thesis (Ph.D.)--Columbia University, 2018.
일반주기 Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Elizabeth M. C. Hillman.
요약Understanding the relationship between neural activity and cortical hemodynamics, or neurovascular coupling is the foundation to interpret neuroimaging signals such as functional magnetic resonance imaging (fMRI) which measure local changes in h
요약To directly assess the cortical neurovascular coupling, simultaneous recordings of neural and hemodynamic activity were imaged by wide-field optical mapping (WFOM) over the bilateral dorsal surface of the mouse brain through a bilateral thinned-
요약A linear model between neural and hemodynamic signals was used to fit spatiotemporal hemodynamics can be predicted by convolving local fluorescence changes with hemodynamic response functions derived through both deconvolution and gamma-variate
일반주제명Biomedical engineering.
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