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Movement of the Escherichia coli RNA Polymerase Clamp Modulates Intrinsic Transcription Termination
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Movement of the Escherichia coli RNA Polymerase Clamp Modulates Intrinsic Transcription Termination. |
| 개인저자 | Bellecourt, Michael J. |
| 단체저자명 | The University of Wisconsin - Madison. Biochemistry-ALS. |
| 발행사항 | [S.l.]: The University of Wisconsin - Madison., 2018. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
| 형태사항 | 180 p. |
| 기본자료 저록 | Dissertation Abstracts International 80-01B(E). Dissertation Abstract International |
| ISBN | 9780438357532 |
| 학위논문주기 | Thesis (Ph.D.)--The University of Wisconsin - Madison, 2018. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Adviser: Robert C. Landick. |
| 요약 | Cellular organisms use RNA polymerases (RNAPs) to express genes through the process of transcription. Accurate and timely RNA synthesis requires regulation of all steps of a complex transcription cycle, a regulatory framework involving the caref |
| 요약 | Prior to my studies, the role of nucleic-acid sequence and structure in these mechanisms were well-characterized, but the role of protein conformation changes were largely unknown. To investigate how movements by the RNAP clamp affected intrinsi |
| 요약 | My studies also determined how the transcription factor NusG promotes Rho-dependent termination. After binding C-rich RNAs in its secondary site, the Rho ring makes small amino acid rearrangements in its C-terminal domain to induce ring closure. |
| 일반주제명 | Biochemistry. Molecular biology. Microbiology. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
