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Investigation of the Role of FOXM1 in the Development of Intimal Hyperplasia
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Investigation of the Role of FOXM1 in the Development of Intimal Hyperplasia. |
| 개인저자 | Franco, Sarah. |
| 단체저자명 | The University of Wisconsin - Madison. Cellular & Molecular Pathology. |
| 발행사항 | [S.l.]: The University of Wisconsin - Madison., 2018. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
| 형태사항 | 127 p. |
| 기본자료 저록 | Dissertation Abstracts International 80-01B(E). Dissertation Abstract International |
| ISBN | 9780438359680 |
| 학위논문주기 | Thesis (Ph.D.)--The University of Wisconsin - Madison, 2018. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Adviser: Bo Liu. |
| 요약 | Vascular smooth muscle cell (SMC) proliferation and survival are key contributors to the initiation and progression of vascular diseases including restenosis. Forkhead Box M1 (FOXM1) is a proliferation-associated transcription factor shown to pl |
| 요약 | In Chapter 2, we utilize the rat carotid balloon injury model to characterize the expression of FOXM1 in the vascular wall. To the best of our knowledge, we are the first to report an upregulation of FOXM1 in neointimal SMCs following balloon in |
| 요약 | In sum, the data generated in my thesis provide foundational evidence that FOXM1 is an important player in SMC response to vascular injury as well as SMC viability. With further understanding of the mechanistic role of FOXM1 in vascular diseases |
| 일반주제명 | Cellular biology. Pathology. Molecular biology. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
