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Childhood Emotional Abuse and Neuroendocrine Stress Systems in Depression: A Possible Role for Corticomotor Circuitry
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Childhood Emotional Abuse and Neuroendocrine Stress Systems in Depression: A Possible Role for Corticomotor Circuitry. |
| 개인저자 | Frost, Carlton P., VI. |
| 단체저자명 | The University of Wisconsin - Madison. Neuroscience. |
| 발행사항 | [S.l.]: The University of Wisconsin - Madison., 2018. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
| 형태사항 | 121 p. |
| 기본자료 저록 | Dissertation Abstracts International 79-11B(E). Dissertation Abstract International |
| ISBN | 9780438079281 |
| 학위논문주기 | Thesis (Ph.D.)--The University of Wisconsin - Madison, 2018. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Advisers: Heather C. Abercrombie |
| 요약 | The activity of neuroendocrine stress systems, and their effects on memory formation & neuroplasticity, are altered in depression. Research in animal models shows early life adversity alters corticosteroids' effects on memory formation and neuro |
| 요약 | In a double-blind crossover study, functional magnetic resonance imaging (fMRI) was used to assess the neural correlates of the effects of cortisol administration (CORT), vs Placebo, on memory formation for emotional pictures. In addition, I use |
| 요약 | Only in women with history of severe EA, CORT eliminated the relation between depression severity and negative memory bias by normalizing recall for pleasant stimuli. These women showed a related increase in BOLD activation in cortical premotor |
| 요약 | Thus, I demonstrate evidence of distinct neurocognitive responses to acute cortisol elevation in depressed women with history of EA, who may comprise an etiologically distinct subtype of depression, and whose emotional learning is partly normali |
| 일반주제명 | Neurosciences. Psychology. Endocrinology. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
