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Precision Medicine in Atrial Fibrillation: A Risk Model for Management with Dabigatran v. Warfarin

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서명/저자사항Precision Medicine in Atrial Fibrillation: A Risk Model for Management with Dabigatran v. Warfarin.
개인저자Ader, Jeremy.
단체저자명Yale University. Yale School of Medicine.
발행사항[S.l.]: Yale University., 2018.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2018.
형태사항75 p.
기본자료 저록Dissertation Abstracts International 79-11B(E).
Dissertation Abstract International
ISBN9780438132801
학위논문주기Thesis (M.D.)--Yale University, 2018.
일반주기 Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Adviser: Nihar R. Desai.
요약The Precision Medicine Initiative aims to advance Medicine from "one-size-fits-all" treatments to more individualized approaches. Clinical trials evaluate treatments by analyzing average outcomes, and thus risk overlooking potential differences
요약We analyzed the Randomized Evaluation of Long-Term Anticoagulation Therapy (RELY) trial of dabigatran versus warfarin in patients with atrial fibrillation, to determine if the application of multivariate predictive models could demonstrate heter
요약These findings demonstrate heterogeneity of treatment effect in the RE-LY trial, and the ability of multivariate risk models to identify distinct treatment risks for individual patients. Such models could be used in clinical practice provide pat
일반주제명Medicine.
Epidemiology.
언어영어
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