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The Functional Role of Naturally Occurring Antibodies Against HIV-1 in Human Genital Mucosa
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | The Functional Role of Naturally Occurring Antibodies Against HIV-1 in Human Genital Mucosa. |
| 개인저자 | Kadasia, Kadryn D. |
| 단체저자명 | Boston University. Molecular and Translational Medicine GMS. |
| 발행사항 | [S.l.]: Boston University., 2018. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
| 형태사항 | 229 p. |
| 기본자료 저록 | Dissertation Abstracts International 79-10B(E). Dissertation Abstract International |
| ISBN | 9780438066991 |
| 학위논문주기 | Thesis (Ph.D.)--Boston University, 2018. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Advisers: Deborah J. Anderson |
| 요약 | Sexual transmission of the Human Immunodeficiency Virus Type 1 (HIV-1) accounts for the majority of newly acquired infections. Vaccination efforts have induced only modest protection in HIV clinical trials. HIV-1 induces a robust local immune re |
| 요약 | This study focused on HIV-specific antibody responses in the male genital tract (MGT), which is underexplored. We characterized antibody subclasses and specificities in genital tract secretions (seminal plasma, urethral secretions) and blood fro |
| 요약 | To explore cell-dependent activities of HIV-specific antibodies in genital mucosa we surveyed Fc receptor expression in mucosal epithelial tissue. The IgG-engaging neonatal Fc receptor (FcRn), the IgA receptor FcalphaRI and the high-affinity int |
| 일반주제명 | Immunology. Medicine. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
