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Genomic Analysis and Examination of Innate Antiviral Immunity in the Egyptian Rousette Bat
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Genomic Analysis and Examination of Innate Antiviral Immunity in the Egyptian Rousette Bat. |
| 개인저자 | Pavlovich, Stephanie Sarah. |
| 단체저자명 | Boston University. Microbiology. |
| 발행사항 | [S.l.]: Boston University., 2018. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
| 형태사항 | 201 p. |
| 기본자료 저록 | Dissertation Abstracts International 79-11B(E). Dissertation Abstract International |
| ISBN | 9780438067523 |
| 학위논문주기 | Thesis (Ph.D.)--Boston University, 2018. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Adviser: Thomas B. Kepler. |
| 요약 | Bats asymptomatically host a number of viruses that are the cause of recently emergent infectious diseases in humans. While the mechanisms underlying this asymptomatic infection are currently not known, studies of sequenced bat genomes help unco |
| 요약 | We observed an unusual expansion of the NKG2/CD94 natural killer (NK) cell receptor gene families in Egyptian rousette bats relative to other species, and found genomic evidence of unique features and expression of these receptors that may resul |
| 요약 | Taken together, these results show that multiple bats, including the ERB, have expanded and diversified numerous antiviral loci, and potentially developed unique adaptations in NK cell receptor signaling, and type I IFN responses. The concerted |
| 일반주제명 | Immunology. Genetics. Virology. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
