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Mechanistic Investigation of (DHQD)2PHAL Catalysis in Chlorination and Dihydroxylation Reactions Using a Naphthalene-Based Analogue

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서명/저자사항Mechanistic Investigation of (DHQD)2PHAL Catalysis in Chlorination and Dihydroxylation Reactions Using a Naphthalene-Based Analogue.
개인저자Grant, Calvin.
단체저자명Michigan State University. Chemistry.
발행사항[S.l.]: Michigan State University., 2018.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2018.
형태사항299 p.
기본자료 저록Dissertation Abstracts International 79-12B(E).
Dissertation Abstract International
ISBN9780438150584
학위논문주기Thesis (Ph.D.)--Michigan State University, 2018.
일반주기 Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Babak Borhan.
요약This dissertation is composed of three different projects, each discussed in a chapter. Following are short descriptions of the contained chapters.
요약Because of the low financial potential gains in antimicrobial drug development, companies have not invested into the area, relying on naturally occurring compounds found within the last twenty to thirty years to keep the microbes at bay. In the
요약In another study, discussed in chapter two, addresses a total synthesis of Alexine, a polyhydroxylated pyrrolizidine found to exhibit antiretroviral activity. While most syntheses of this family of pyrrolizidines utilized amino acids or sugars a
요약In the final chapter, for which the dissertation has been titled, new advancements in halofunctionalization that have been uncovered in the Borhan laboratory are further investigated. In particular, the hypothesis regarding the enantioselectivit
일반주제명Chemistry.
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