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Risk Factors for Transmission of Multidrug-Resistant Organisms and Acquisition of Healthcare-Associated Infections

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서명/저자사항Risk Factors for Transmission of Multidrug-Resistant Organisms and Acquisition of Healthcare-Associated Infections.
개인저자Jackson, Sarah S.
단체저자명University of Maryland, Baltimore. Epidemiology and Preventive Medicine.
발행사항[S.l.]: University of Maryland, Baltimore., 2018.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2018.
형태사항152 p.
기본자료 저록Dissertation Abstracts International 79-10B(E).
Dissertation Abstract International
ISBN9780438028807
학위논문주기Thesis (Ph.D.)--University of Maryland, Baltimore, 2018.
일반주기 Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Advisers: Anthony D. Harris
요약Background: Healthcare-associated infections (HAI) increase hospitalized patients' morbidity and mortality. In order to prevent the spread of HAI among patients in the healthcare setting, a better understanding of transmission dynamics and how p
요약Objectives: To estimate the association between patients' bacterial burden of vancomycin-resistant Enterococcus (VRE) and transmission to others and to build risk adjustment models taking into account patient case-mix for a more accurate compari
요약Methods: Using a prospective cohort design, quantitative cultures (perianal, skin, and stool samples) were obtained from VRE-colonized ICU patients at the University of Maryland Medical Center. The association between patient bacterial burden an
요약Results: There were 71 transmission events among 479 HCW-patient interactions. VRE transmission was associated with VRE burden on the perianal swab (OR: 1.37 [95% CI 1.19, 1.57])
요약Conclusions: Our first study shows that ICU patients with higher bacterial burden are more likely to transfer VRE to HCWs. Our second study demonstrates the importance of including comorbidities in risk adjustment models. These findings have imp
일반주제명Epidemiology.
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